The effect of asparagine and adenine on the glutamine requirement for growth of human peripheral lymphocytes.
نویسندگان
چکیده
Quantitative growth responses of lymphocytes directly isolated from individual subjects in a newly developed chemically-defined, protein-free medium are used to demonstrate that supplements of both L-asparagine and a purine source, but neither alone, significantly reduce the quantitative requirement for L-glutamine for growth. This system is useful for exploring individual differences in quantitative glutamine requirements and adequacy of asparagine and purine biosynthesis.
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ورودعنوان ژورنال:
- Biochemical and biophysical research communications
دوره 164 3 شماره
صفحات -
تاریخ انتشار 1989